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The available data is one short-duration clinical trial in surgical patients (which found it well tolerated) and early pharmacokinetic work in healthy volunteers that did not flag acute harms

Oral supplements have to pass through the digestive system and may not be absorbed efficiently, especially in people with gastrointestinal conditions like celiac, Crohns, or gastritis

Review meaningful changes with the prescribing clinician

This allows the companies that produce them to set high prices without competition

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